You know, I built a MUSH not too long ago based on my old hometown of Newark, Delaware. (I know, it sounds crap, but trust me, it was glorious. Everything stretching from Elkton, Maryland to Kirkwood Highway was lovingly rendered in Zork-like text.)
I don't think it would be too hard to set up something like that, perhaps as an interactive "Site" where people could opt classes like Doctor, Agent, or even an SCP (though that last one would have to have some fairly inventive rules governing gameplay, or at the very least a strong agreement in a social RPG setting not to powergame).
Also neat would be to have a version of the database searchable from inside the game (probably MOO style would be best for this due to object-oriented programming structure which can spider other mediums, so you could simply cull from the current web database, etc.).
We could have feature characters, too. KPC for example would get obvious first dibs on his creations, and so forth.
I'd start setting it all up now but unfortunately I have to sleep occasionally.