a limestone obelisk that essentially enhances latent anger, bigotry, and hatred in people
We've seen a lot of variants of this sort of item before, usually things like flags or political documents. They pretty much never go well due to predictability and the mentioned insensitivity isssue.
its effect has a much larger radius than previously expected, leading to the creation of a terrorist group that proceeds to wreak havoc on innocent civilians.
Generally, an SCP object's effect forcing someone to do something tends to be a bit of a lame narrative, since things are more interesting if there's a struggle involved, and/or if the people instead do terrible things of their own volition rather than just because the author needs them to for the story to work. Consider reading through the further discussion on the narrative issues of compulsion and addiction effects.
What I want to know is if I can respectfully and tactfully approach this topic.
I mean… there might be a way to handle this tactfully, but that doesn't mean that it would necessarily make a good SCP. Explaining terrorist actions away with "an anomaly made them do it" is kind of overly simplistic and I'm not sure if the concept would be able to support itself.
Maaaaaaaaaybe it would be workable as a tale detailing the Foundation's investigation of the anomaly, but I can't really guarantee anything here. We would need to know more background.
Out of curiosity, why do you want to use this approach? What about this sort of idea interests you, and what are your goals for audience reaction to the eventual piece?